Fibre & Satiety
Glucomannan and other viscous fibres that slow gastric emptying and increase fullness β the closest mechanical parallel to how GLP-1 drugs work.
Viscous, gel-forming fibres like glucomannan (konjac root) expand in the stomach and slow the rate food moves into the small intestine. Thatβs mechanically the closest a nutraceutical gets to what a GLP-1 receptor agonist does pharmacologically β both increase the feeling of fullness and slow gastric emptying, just through completely different pathways (mechanical bulk versus receptor signalling).
Fibre supplements are also one of the most evidence-backed categories here for general satiety and modest weight-management support, with a long safety track record.